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The absolute number of monocytes ( Supplementary Table 2 ) dropped to one fifth of the initial level immediately after LPS administration and remained at this level for 3 days, before recovering until 7 d pi

Early studies using genetic models, alongside analyses of human patients with mutations suggested that NF-B signaling played a role in establishing long-term protective T cell memory pools (159, 160), However, the lack of inducible T cell-restricted NF-B models has made it difficult to determine whether the observed defects in memory T cell levels result from early issues with T cell priming or proliferation, or from later problems in differentiation and survival

doi: 10.1016/j.intimp.2024.112819